Experimental active and passive dosimetry systems for the NASA Skylab program

Active and passive dosimetry instrumentation to measure absorbed dose, charged particle spectra, and linear energy transfer spectra inside the command module and orbital workshop on the Skylab program were developed and tested. The active dosimetry system consists of one integral unit employing both a tissue equivalent ionization chamber and silicon solid state detectors. The instrument measures dose rates from 0.2 millirad/hour to 25 rads/hour, linear energy transfer spectra from 2.8 to 42.4 Kev/micron, and the proton and alpha particle energy spectra from 0.5 to 75 Mev. The active dosimeter is equipped with a portable radiation sensor for use in astronaut on-body and spacecraft shielding surveys during passage of the Skylab through significant space radiations. Data are transmitted in real time or are recorded by onboard spacecraft tape recorder for rapid evaluation of the radiation levels. The passive dosimetry systems consist of twelve (12) hard-mounted assemblies, each containing a variety of passive radiation sensors which are recoverable at the end of the mission for analysis

Space shuttle: Aerodynamic characteristics of a composite booster/040A orbiter launch configuration with fin and booster body configuration effect contribution

An investigation was made of the fin configuration and booster body configuration effects on a composite booster/040A orbiter launch configuration. Aerodynamic performance and stability characteristics in pitch and yaw were obtained. Configurations tested included two stepped cylindrical bodies of different lengths with a conical nose, four fin shapes of various sizes and aspect ratios mounted in different positions around the base of the bodies, two base flare angles and three 040A orbiter configurations. The orbiter variations included a tailless configuration and two tail sizes. A tailless booster launch configuration with deflected petals (expanded flare sectors) was also tested. The model scale was 0.003366. Data were converted to coefficient form in near real time, punched on cards, and tabulated. The cards used in conjunction with a Benson-Lehner plotter were used to provide plotted data. At the end of the test, tabulated input forms were completed for the SADSAC computer program to aid in publishing the final test data report

Whole-cell Escherichia coli lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical production

Many high-value added recombinant proteins, such as therapeutic glycoproteins, are produced using mammalian cell cultures. In order to optimise the productivity of these cultures it is important to monitor cellular metabolism, for example the utilisation of nutrients and the accumulation of metabolic waste products. One metabolic waste product of interest is lactic acid (lactate), overaccumulation of which can decrease cellular growth and protein production. Current methods for the detection of lactate are limited in terms of cost, sensitivity, and robustness. Therefore, we developed a whole-cell Escherichia coli lactate biosensor based on the lldPRD operon and successfully used it to monitor lactate concentration in mammalian cell cultures. Using real samples and analytical validation we demonstrate that our biosensor can be used for absolute quantification of metabolites in complex samples with high accuracy, sensitivity and robustness. Importantly, our whole-cell biosensor was able to detect lactate at concentrations more than two orders of magnitude lower than the industry standard method, making it useful for monitoring lactate concentrations in early phase culture. Given the importance of lactate in a variety of both industrial and clinical contexts we anticipate that our whole-cell biosensor can be used to address a range of interesting biological questions. It also serves as a blueprint for how to capitalise on the wealth of genetic operons for metabolite sensing available in Nature for the development of other whole-cell biosensors

Forebody and vertical stabilizer effects on directional stability of a reusable LOX/RP (061) booster AR 12161-2

Results are presented of a wind tunnel test on the directional stability of space shuttle booster configurations. The test was conducted at the 14-inch trisonic tunnel starting 6 December 1971 and continued through 11 December 1971 for a total of 66 occupancy hours. Configurations tested included a cylindrical body with two axisymmetrical noses, one with and without canopy, one delta wing, located in two positions, five vertical tails (including a V tail), two having split rudders, ventral fins, two sets of chines, three airbreathing engine pods, and rocket engine shrouds. The model scale was 0.003366

Government controls of American correspondents in China

The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.Title from title screen of research.pdf file (viewed on August 10, 2009)Thesis (M.A.) University of Missouri-Columbia 2008.This study examined the controls placed on American news correspondents by the Chinese government during an unprecedented period of transition in China's history. Correspondents were interviewed in Beijing to identify the controls they face; how they handle those controls and the effects those controls have on their work. The results show that despite a recent expansion of freedom for the foreign media in China, many restrictions, most of which manifest as official actions, often frustrate the work of correspondents. Authoritarian controls and attempts to influence foreign reporters through public relations manipulation reveal a campaign by the Chinese government to shape its global image through international news. The methods used by correspondents to handle controls indicate an effort to circumvent the restrictions and stem from a concept of the journalist's role in society that is at odds with authoritarian press models. Nonetheless, government controls and counteraction methods have enough of an impact on correspondents that news content may be affected. The data are considered within the context of China's economic and technological transformation, which is found to both help and hinder the government's control efforts and significantly aid the work of correspondents..Includes bibliographical reference

How Much of the Web Is Archived?

Although the Internet Archive's Wayback Machine is the largest and most well-known web archive, there have been a number of public web archives that have emerged in the last several years. With varying resources, audiences and collection development policies, these archives have varying levels of overlap with each other. While individual archives can be measured in terms of number of URIs, number of copies per URI, and intersection with other archives, to date there has been no answer to the question "How much of the Web is archived?" We study the question by approximating the Web using sample URIs from DMOZ, Delicious, Bitly, and search engine indexes; and, counting the number of copies of the sample URIs exist in various public web archives. Each sample set provides its own bias. The results from our sample sets indicate that range from 35%-90% of the Web has at least one archived copy, 17%-49% has between 2-5 copies, 1%-8% has 6-10 copies, and 8%-63% has more than 10 copies in public web archives. The number of URI copies varies as a function of time, but no more than 31.3% of URIs are archived more than once per month.Comment: This is the long version of the short paper by the same title published at JCDL'11. 10 pages, 5 figures, 7 tables. Version 2 includes minor typographical correction

Global climate change and tree nutrition: effects of elevated CO2 and temperature

Although tree nutrition has not been the primary focus of large climate change experiments on trees, we are beginning to understand its links to elevated atmospheric CO2 and temperature changes. This review focuses on the major nutrients, namely N and P, and deals with the effects of climate change on the processes that alter their cycling and availability. Current knowledge regarding biotic and abiotic agents of weathering, mobilization and immobilization of these elements will be discussed. To date, controlled environment studies have identified possible effects of climate change on tree nutrition. Only some of these findings, however, were verified in ecosystem scale experiments. Moreover, to be able to predict future effects of climate change on tree nutrition at this scale, we need to progress from studying effects of single factors to analysing interactions between factors such as elevated CO2, temperature or water availability

Topological Qubit Design and Leakage

We examine how best to design qubits for use in topological quantum computation. These qubits are topological Hilbert spaces associated with small groups of anyons. Op- erations are performed on these by exchanging the anyons. One might argue that, in order to have as many simple single qubit operations as possible, the number of anyons per group should be maximized. However, we show that there is a maximal number of particles per qubit, namely 4, and more generally a maximal number of particles for qudits of dimension d. We also look at the possibility of having topological qubits for which one can perform two-qubit gates without leakage into non-computational states. It turns out that the requirement that all two-qubit gates are leakage free is very restrictive and this property can only be realized for two-qubit systems related to Ising-like anyon models, which do not allow for universal quantum computation by braiding. Our results follow directly from the representation theory of braid groups which means they are valid for all anyon models. We also make some remarks on generalizations to other exchange groups.Comment: 13 pages, 3 figure